Human CCL23 (C-C Motif Chemokine 23) Antibody Pair (STJAP00169)

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STJAP00169-50
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Host: Goat/Goat
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This CCL23 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Polyclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Antigen Affinity.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: CCL23
Gene ID: 6368
Uniprot ID: CCL23_HUMAN
Immunogen: Capture immunogen: Recombinant Human CCL23 protein.
Detection Immunogen: Recombinant Human CCL23 protein.
Post Translational Modifications The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23.
Protein Name C-C Motif Chemokine 23
Ck-Beta-8
Ckb-8
Macrophage Inflammatory Protein 3
Mip-3
Myeloid Progenitor Inhibitory Factor 1
Mpif-1
Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99
Database Links Reactome: R-HSA-416476 P55773-2
Reactome: R-HSA-418594 P55773-2
Reactome: R-HSA-444473 P55773-2
Cellular Localisation Secreted
Alternative Antibody Pair Names C-C Motif Chemokine 23 antibody pair
Ck-Beta-8 antibody pair
Ckb-8 antibody pair
Macrophage Inflammatory Protein 3 antibody pair
Mip-3 antibody pair
Myeloid Progenitor Inhibitory Factor 1 antibody pair
Mpif-1 antibody pair
Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 antibody pair
CCL23 antibody pair
MIP3 antibody pair
MPIF1 antibody pair
SCYA23 antibody pair

Information sourced from Uniprot.org

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