Human CCL19/MIP-3-beta protein (Recombinant) (N-His) (STJP005909)

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STJP005909
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL19/MIP-3-beta-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL19
Gene ID: 6363
Uniprot ID: CCL19_HUMAN
Immunogen Region: Gly22-Ser98
Immunogen: Homo sapiens (Human)
Function May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 19
Beta-Chemokine Exodus-3
Ck Beta-11
Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine
Ebi1 Ligand Chemokine
Elc
Macrophage Inflammatory Protein 3 Beta
Mip-3-Beta
Small-Inducible Cytokine A19
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 19 protein
Beta-Chemokine Exodus-3 protein
Ck Beta-11 protein
Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine protein
Ebi1 Ligand Chemokine protein
Elc protein
Macrophage Inflammatory Protein 3 Beta protein
Mip-3-Beta protein
Small-Inducible Cytokine A19 protein
CCL19 protein
ELC protein
MIP3B protein
SCYA19 protein

Information sourced from Uniprot.org

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