Name: Human CCL19/MIP-3 beta protein (Recombinant) (C-His) (STJP001992)
SKU: STJP001992
Availability: InStock

Human CCL19/MIP-3 beta protein (Recombinant) (C-His) (STJP001992)

SKU:

STJP001992

£139.50 - £493.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.1 EU/Mu g

Gene Symbol:	CCL19
Gene ID:	6363
Uniprot ID:	CCL19_HUMAN
Immunogen Region:	Gly22-Ser98
Immunogen:	Recombinant Human CCL19/MIP-3 beta Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly22-Ser98) of human CCL19/MIP-3 beta (Accession #NP_006265.1) fused with a 6×His tag at the C-terminus.
Immunogen Sequence:	GTNDAEDCCLSVTQKPIPGY IVRNFHYLLIKDGCRVPAVV FTTLRGRQLCAPPDQPWVER IIQRLQRTSAKMKRRSS

Function	May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name	C-C Motif Chemokine 19 Beta-Chemokine Exodus-3 Ck Beta-11 Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine Ebi1 Ligand Chemokine Elc Macrophage Inflammatory Protein 3 Beta Mip-3-Beta Small-Inducible Cytokine A19
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-418594 Reactome: R-HSA-6783783
Cellular Localisation	Secreted
Alternative Protein Names	C-C Motif Chemokine 19 protein Beta-Chemokine Exodus-3 protein Ck Beta-11 protein Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine protein Ebi1 Ligand Chemokine protein Elc protein Macrophage Inflammatory Protein 3 Beta protein Mip-3-Beta protein Small-Inducible Cytokine A19 protein CCL19 protein ELC protein MIP3B protein SCYA19 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP001983	Human FSH Beta protein (Recombinant) (C-His) (STJP001983)	HEK293 cells
STJP002836	Human CCL3/MIP-1 alpha protein (Recombinant) (C-His) (STJP002836)	HEK293 cells
STJP001253	Human Catenin beta-1 protein (Recombinant) (C-His) (STJP001253)	E. coli
STJP002079	Human Klotho beta/KLB protein (Recombinant) (C-His) (STJP002079)	HEK293 cells

Human CCL19/MIP-3 beta protein (Recombinant) (C-His) (STJP001992)