Human CCKBR/CCK2-R protein (Recombinant) (N-GST & C-His) (STJP015144)

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STJP015144
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCKBR/CCK2-R-N-GST & C-His protein was developed from e.coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: 0
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-193°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: CCKBR
Gene ID: 887
Uniprot ID: GASR_HUMAN
Immunogen Region: Arg243-Arg333
Immunogen: Homo sapiens (Human)
Function Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
Protein Name Gastrin/Cholecystokinin Type B Receptor
Cck-B Receptor
Cck-Br
Cholecystokinin-2 Receptor
Cck2-R
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-881907
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Gastrin/Cholecystokinin Type B Receptor protein
Cck-B Receptor protein
Cck-Br protein
Cholecystokinin-2 Receptor protein
Cck2-R protein
CCKBR protein
CCKRB protein

Information sourced from Uniprot.org

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