Tissue Specificity | |
Post Translational Modifications | |
Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. |
Protein Name | Kynurenine--Oxoglutarate Transaminase 1Cysteine-S-Conjugate Beta-LyaseGlutamine Transaminase KGtkGlutamine--Phenylpyruvate TransaminaseKynurenine Aminotransferase 1Kynurenine Aminotransferase IKatiKynurenine--Oxoglutarate Transaminase I |
Database Links | Reactome: R-HSA-71240Reactome: R-HSA-8964208Reactome: R-HSA-8964539 |
Cellular Localisation | CytoplasmCytosol |
Alternative ELISA Names | Kynurenine--Oxoglutarate Transaminase 1 ELISA kitCysteine-S-Conjugate Beta-Lyase ELISA kitGlutamine Transaminase K ELISA kitGtk ELISA kitGlutamine--Phenylpyruvate Transaminase ELISA kitKynurenine Aminotransferase 1 ELISA kitKynurenine Aminotransferase I ELISA kitKati ELISA kitKynurenine--Oxoglutarate Transaminase I ELISA kitKYAT1 ELISA kitCCBL1 ELISA kit |
output | |
Information sourced from Uniprot.org