Human CBX1 protein (Recombinant) (N-His) (STJP007765)

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STJP007765
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CBX1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CBX1
Gene ID: 10951
Uniprot ID: CBX1_HUMAN
Immunogen Region: Glu24-Leu168
Immunogen: Homo sapiens (Human)
Post Translational Modifications Not phosphorylated. Ubiquitinated.
Function Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Protein Name Chromobox Protein Homolog 1
Hp1hsbeta
Heterochromatin Protein 1 Homolog Beta
Hp1 Beta
Heterochromatin Protein P25
M31
Modifier 1 Protein
P25beta
Database Links Reactome: R-HSA-9609690
Cellular Localisation Nucleus
Unassociated With Chromosomes During Mitosis
Alternative Protein Names Chromobox Protein Homolog 1 protein
Hp1hsbeta protein
Heterochromatin Protein 1 Homolog Beta protein
Hp1 Beta protein
Heterochromatin Protein P25 protein
M31 protein
Modifier 1 Protein protein
P25beta protein
CBX1 protein
CBX protein

Information sourced from Uniprot.org

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