• Human Cathepsin S protein (Active Recombinant) (C-His) (STJP000955)

Human Cathepsin S protein (Active Recombinant) (C-His) (STJP000955)

SKU:
STJP000955

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Active Recombinant-Human Cathepsin S-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 50mM MES, 100mM NaCl, pH6.5. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2. The specific activity is >1390 pmol/min/Mu g.
Gene Symbol: CTSS
Gene ID: 1520
Uniprot ID: CATS_HUMAN
Immunogen Region: Gln17-Ile331
Immunogen: Recombinant Human Cathepsin S Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln17-Ile331) of human Cathepsin S/CTSS (Accession #NP_004070.3) fused with an 8×His tag at the C-terminus.
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Protein Name Cathepsin S
Database Links Reactome: R-HSA-1236977
Reactome: R-HSA-1474228
Reactome: R-HSA-1679131
Reactome: R-HSA-2022090
Reactome: R-HSA-2132295
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Secreted
Cytoplasmic Vesicle
Phagosome
Alternative Protein Names Cathepsin S protein
CTSS protein

Information sourced from Uniprot.org

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