| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CARD18-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARD18 |
| Gene ID: | 59082 |
| Uniprot ID: | CAR18_HUMAN |
| Immunogen Region: | 1-90aa |
| Accession Number: | NP_067546 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH |
| Tissue Specificity | Primarily expressed in the heart and placenta. |
| Function | Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. |
| Protein Name | Caspase Recruitment Domain-Containing Protein 18Caspase-1 Inhibitor Iceberg |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Caspase Recruitment Domain-Containing Protein 18 proteinCaspase-1 Inhibitor Iceberg proteinCARD18 proteinICEBERG proteinUNQ5804 proteinPRO19611 protein |
Information sourced from Uniprot.org