Human CARD17 protein (Recombinant) (His-Tag) (STJP018414)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CARD17-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CARD17PUniprot ID=CAR17_HUMAN" |
| Accession Number | NP_001007233 |
| Immunogen | Human |
| Immunogen Region | 1-110aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
| Protein Name | Putative Caspase Recruitment Domain-Containing Protein 17pCaspase-1 Inhibitor IncaInhibitory Caspase Recruitment Domain Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Putative Caspase Recruitment Domain-Containing Protein 17p proteinCaspase-1 Inhibitor Inca proteinInhibitory Caspase Recruitment Domain Protein proteinCARD17P proteinCARD17 proteinINCA protein |
Information sourced from Uniprot.org