Human CARD17 protein (Recombinant) (His-Tag) (STJP018414)

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STJP018414
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CARD17-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CARD17PUniprot ID=CAR17_HUMAN"
Immunogen Region: 1-110aa
Accession Number: NP_001007233
Immunogen: Human
Immunogen Sequence: MADKVLK EKRKQFIRSV GEGTINGLLG ELLETRVLSQ EEIEIVKCEN ATVMDKARAL LDSVIRKGAP ACQICITYIC EEDSHLAGTL GLSAGPTSGN HLTTQDSQIV LPS
Tissue Specificity Ubiquitous.
Function Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Protein Name Putative Caspase Recruitment Domain-Containing Protein 17p
Caspase-1 Inhibitor Inca
Inhibitory Caspase Recruitment Domain Protein
Cellular Localisation Cytoplasm
Alternative Protein Names Putative Caspase Recruitment Domain-Containing Protein 17p protein
Caspase-1 Inhibitor Inca protein
Inhibitory Caspase Recruitment Domain Protein protein
CARD17P protein
CARD17 protein
INCA protein

Information sourced from Uniprot.org

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