| Short Description : | Active Recombinant-Human Carbonic anhydrase 9-C-His&Avi protein was developed in hek293 cells using the region Gln38-Asp414. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its esterase activity. The specific activity is >84 pmoles/min/Mu g, as measured with 1 mM 4-Nitrophenyl acetate and 1 Mu g enzyme at 400 nm in 100 Mu L of 12.5 mM Tris, 75 mM NaCl, pH 7.5. |
| Determination Method: | Please contact us for more information. |
| Gene Symbol: | CA9 |
| Gene ID: | 768 |
| Uniprot ID: | CAH9_HUMAN |
| Immunogen: | Recombinant Human Carbonic anhydrase 9 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln38-Asp414) of human Carbonic Anhydrase IX/CA9 (Accession #NP_001207.2) fused with a 6×His, Avi tag at the |
| Immunogen Region: | Gln38-Asp414 |
| Immunogen Sequence: | QRLPRMQEDSPLGGGSSGED DPLGEEDLPSEEDSPREEDP PGEEDLPGEEDLPGEEDLPE VKPKSEEEGSLKLEDLPTVE APGDPQEPQNNAHRDKEGDD QSHWRYGGDPPWPRVSPACA GRFQSPVDIRPQLAAFCPAL RPLELLGFQLPPLPELRLRN NGHSVQLTLPPGLEMALGPG REYRALQLHLHWGAAGRPGS EHTVEGHRFPAEIHVVHLST AFARVDEALGRPGGLAVLA |
| Post Translational Modifications | Asn-346 bears high-mannose type glycan structures. |
| Function | Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). |
| Protein Name | Carbonic Anhydrase 9Carbonate Dehydratase IxCarbonic Anhydrase IxCa-IxCaixMembrane Antigen MnP54/58nRenal Cell Carcinoma-Associated Antigen G250Rcc-Associated Antigen G250Pmw1 |
| Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-1475029 |
| Cellular Localisation | NucleusNucleolusCell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillus MembraneFound On The Surface Microvilli And In The NucleusParticularly In Nucleolus |
| Alternative Protein Names | Carbonic Anhydrase 9 proteinCarbonate Dehydratase Ix proteinCarbonic Anhydrase Ix proteinCa-Ix proteinCaix proteinMembrane Antigen Mn proteinP54/58n proteinRenal Cell Carcinoma-Associated Antigen G250 proteinRcc-Associated Antigen G250 proteinPmw1 proteinCA9 proteinG250 proteinMN protein |
Information sourced from Uniprot.org
