Human CAPN6 protein (Recombinant) (N-His) (STJP006357)

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STJP006357
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CAPN6-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CAPN6
Gene ID: 827
Uniprot ID: CAN6_HUMAN
Immunogen Region: Leu26-Arg495
Immunogen: Homo sapiens (Human)
Function Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.
Protein Name Calpain-6
Calpain-Like Protease X-Linked
Calpamodulin
Calpm
Database Links Reactome: R-HSA-1474228
Cellular Localisation Cytoplasm
Perinuclear Region
Cytoskeleton
Spindle
During Mitose Associated With The Mitotic Spindle
At Telophase Colocalized To The Midbody Spindle
Alternative Protein Names Calpain-6 protein
Calpain-Like Protease X-Linked protein
Calpamodulin protein
Calpm protein
CAPN6 protein
CALPM protein
CANPX protein

Information sourced from Uniprot.org

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