Tissue Specificity | Ubiquitous. |
Post Translational Modifications | |
Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. |
Protein Name | Calpain-2 Catalytic SubunitCalcium-Activated Neutral Proteinase 2Canp 2Calpain M-TypeCalpain Large Polypeptide L2Calpain-2 Large SubunitMillimolar-CalpainM-Calpain |
Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-8862803 |
Cellular Localisation | CytoplasmCell MembraneTranslocates To The Plasma Membrane Upon Ca(2+) Binding |
Alternative ELISA Names | Calpain-2 Catalytic Subunit ELISA kitCalcium-Activated Neutral Proteinase 2 ELISA kitCanp 2 ELISA kitCalpain M-Type ELISA kitCalpain Large Polypeptide L2 ELISA kitCalpain-2 Large Subunit ELISA kitMillimolar-Calpain ELISA kitM-Calpain ELISA kitCAPN2 ELISA kitCANPL2 ELISA kit |
output | |
Information sourced from Uniprot.org