Human CAMLG protein (Recombinant) (N-His) (STJP004805)

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STJP004805
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CAMLG-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CAMLG
Gene ID: 819
Uniprot ID: CAMLG_HUMAN
Immunogen Region: Gly19-Glu184
Immunogen: Homo sapiens (Human)
Function Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.
Protein Name Guided Entry Of Tail-Anchored Proteins Factor Camlg
Calcium Signal-Modulating Cyclophilin Ligand
Database Links Reactome: R-HSA-9609523
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Guided Entry Of Tail-Anchored Proteins Factor Camlg protein
Calcium Signal-Modulating Cyclophilin Ligand protein
CAMLG protein
CAML protein
GET2 protein

Information sourced from Uniprot.org

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