| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Calcium Activated Nucleotidase 1/CANT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 50mM NaCl |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CANT1 |
| Gene ID: | 124583 |
| Uniprot ID: | CANT1_HUMAN |
| Immunogen Region: | 63-401aa |
| Accession Number: | NP_620148 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMRPAPG RPPTHNAHNW RLGQAPANWY NDTYPLSPPQ RTPAGIRYRI AVIADLDTES RAQEENTWFS YLKKGYLTLS DSGDKVAVEW DKDHGVLESH LAEKGRGMEL SDLIVFNGKL YSVDDRTGVV YQIEGSKAVP WVILSDGDGT VEKGFKAEWL AVKDERLYVG GLGKEWTTTT GDVVNENPEW VKVVGYKGSV DHENWVSN |
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis. |
| Protein Name | Soluble Calcium-Activated Nucleotidase 1Scan-1Apyrase HomologPutative Mapk-Activating Protein Pm09Putative Nf-Kappa-B-Activating Protein 107 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi ApparatusGolgi Stack MembraneCell MembraneProcessed Form: Secreted |
| Alternative Protein Names | Soluble Calcium-Activated Nucleotidase 1 proteinScan-1 proteinApyrase Homolog proteinPutative Mapk-Activating Protein Pm09 proteinPutative Nf-Kappa-B-Activating Protein 107 proteinCANT1 proteinSHAPY protein |
Information sourced from Uniprot.org