Human CACYBP protein (Recombinant) (N-His) (STJP006012)

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STJP006012
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CACYBP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CACYBP
Gene ID: 27101
Uniprot ID: CYBP_HUMAN
Immunogen Region: Ala2-Phe228
Immunogen: Homo sapiens (Human)
Function May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
Protein Name Calcyclin-Binding Protein
Cacybp
Hcacybp
S100a6-Binding Protein
Siah-Interacting Protein
Cellular Localisation Nucleus
Cytoplasm
Cytoplasmic At Low Calcium Concentrations
In Neuroblastoma Cells
After A Retinoic Acid (Ra) Induction And Calcium Increase
It Localizes In Both The Nucleus And Cytoplasm
The Nuclear Fraction May Be Phosphorylated
Alternative Protein Names Calcyclin-Binding Protein protein
Cacybp protein
Hcacybp protein
S100a6-Binding Protein protein
Siah-Interacting Protein protein
CACYBP protein
S100A6BP protein
SIP protein
PNAS-107 protein

Information sourced from Uniprot.org

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