Human CACYBP protein (Recombinant) (His-Tag) (STJP016706)

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STJP016706
£125.50 - £649.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CACYBP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.1M NaCl.
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACYBP
Gene ID: 27101
Uniprot ID: CYBP_HUMAN
Immunogen Region: 1-185aa
Accession Number: NP_001007215
Immunogen: Human
Immunogen Sequence: MQQKSQKKAE LLDNEKPAAV VAPITTGYTV KISNYGWDQS DKFVKIYITL TGVHQVPTEN VQVHFTERSF DLLVKNLNGK SYSMIVNNLL KPISVEGSSK KVKTDTVLIL CRKKVENTRW DYLTQVEKEC KEKEKPSYDT ETDPSEGLMN VLKKIYEDGD DDMKRTINKA WVESREKQAK GDTEF
Post Translational Modifications Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations.
Function May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
Protein Name Calcyclin-Binding Protein
Cacybp
Hcacybp
S100a6-Binding Protein
Siah-Interacting Protein
Database Links
Cellular Localisation Nucleus
Cytoplasm
Cytoplasmic At Low Calcium Concentrations
In Neuroblastoma Cells
After A Retinoic Acid (Ra) Induction And Calcium Increase
It Localizes In Both The Nucleus And Cytoplasm
The Nuclear Fraction May Be Phosphorylated
Alternative Protein Names Calcyclin-Binding Protein protein
Cacybp protein
Hcacybp protein
S100a6-Binding Protein protein
Siah-Interacting Protein protein
CACYBP protein
S100A6BP protein
SIP protein
PNAS-107 protein

Information sourced from Uniprot.org

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