| Short Description : | Recombinant-Human CABP4-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | CABP4 |
| Gene ID: | 57010 |
| Uniprot ID: | CABP4_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ser103-His275 |
| Post Translational Modifications | Phosphorylated. Phosphorylation levels change with the light conditions and regulate the activity. |
| Function | Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages. |
| Protein Name | Calcium-Binding Protein 4Cabp4 |
| Database Links | |
| Cellular Localisation | CytoplasmPresynapseFound In Rod Spherules And Cone Pedicles Of The Presynapses From Both Types Of Photoreceptors |
| Alternative Protein Names | Calcium-Binding Protein 4 proteinCabp4 proteinCABP4 protein |
Information sourced from Uniprot.org