Human C4BPA protein (Recombinant) (N-His) (STJP003637)

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STJP003637
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human C4BPA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: C4BPA
Gene ID: 722
Uniprot ID: C4BPA_HUMAN
Immunogen Region: Pro289-Leu597
Immunogen: Homo sapiens (Human)
Function Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Protein Name C4b-Binding Protein Alpha Chain
C4bp
Proline-Rich Protein
Prp
Database Links Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Protein Names C4b-Binding Protein Alpha Chain protein
C4bp protein
Proline-Rich Protein protein
Prp protein
C4BPA protein
C4BP protein

Information sourced from Uniprot.org