Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human C4BPA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | C4BPA |
Gene ID: | 722 |
Uniprot ID: | C4BPA_HUMAN |
Immunogen Region: | Pro289-Leu597 |
Immunogen: | Homo sapiens (Human) |
Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
Protein Name | C4b-Binding Protein Alpha ChainC4bpProline-Rich ProteinPrp |
Database Links | Reactome: R-HSA-977606 |
Cellular Localisation | Secreted |
Alternative Protein Names | C4b-Binding Protein Alpha Chain proteinC4bp proteinProline-Rich Protein proteinPrp proteinC4BPA proteinC4BP protein |
Information sourced from Uniprot.org