Human C1S protein (Recombinant) (C-His) (STJP006799)

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STJP006799
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human C1S-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: C1S
Gene ID: 716
Uniprot ID: C1S_HUMAN
Immunogen Region: Met1-Asp688
Immunogen: Homo sapiens (Human)
Function C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. Cleaves also IGFBP5 and thereby inhibits the trophic effects of IGF1.
Protein Name Complement C1s Subcomponent
C1 Esterase
Complement Component 1 Subcomponent S Cleaved Into - Complement C1s Subcomponent Heavy Chain - Complement C1s Subcomponent Light Chain
Database Links Reactome: R-HSA-166663
Reactome: R-HSA-173623
Reactome: R-HSA-977606
Alternative Protein Names Complement C1s Subcomponent protein
C1 Esterase protein
Complement Component 1 Subcomponent S Cleaved Into - Complement C1s Subcomponent Heavy Chain - Complement C1s Subcomponent Light Chain protein
C1S protein

Information sourced from Uniprot.org