| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human C-Reactive Protein at 2 Mu g/mL (100 Mu L/well) can bind CRP Rabbit mAb with a linear range of 0.488-6.81 ng/mL. |
| Gene Symbol: | CRP |
| Gene ID: | 1401 |
| Uniprot ID: | CRP_HUMAN |
| Immunogen Region: | Phe17-Pro224 |
| Immunogen: | Recombinant Human C-ReProtein/CRP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe17-Pro224) of human C-Reactive Protein (Accession #NP_000558.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | FGQTDMSRKAFVFPKESDTS YVSLKAPLTKPLKAFTVCLH FYTELSSTRGYSIFSYATKR QDNEILIFWSKDIGYSFTVG GSEILFEVPEVTVAPVHICT SWESASGIVEFWVDGKPRVR KSLKKGYTVGAEASIILGQE QDSFGGNFEGSQSLVGDIGN VNMWDFVLSPDEINTIYLGG PFSPNVLNWRALKYEVQGEV FTKPQLWP |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 |
| Database Links | Reactome: R-HSA-173623 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 proteinCRP proteinPTX1 protein |
Information sourced from Uniprot.org