Human BPNT1 protein (Recombinant) (N-His) (STJP010801)

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STJP010801
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BPNT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BPNT1
Gene ID: 10380
Uniprot ID: BPNT1_HUMAN
Immunogen Region: Met1-Pro308
Immunogen: Homo sapiens (Human)
Function Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate.
Protein Name 3'(2' -5'-Bisphosphate Nucleotidase 1
3'-Phosphoadenosine 5'-Phosphate Phosphatase
Pap Phosphatase
Bisphosphate 3'-Nucleotidase 1
Bpntase 1
Hspip
Inositol-Polyphosphate 1-Phosphatase
Database Links Reactome: R-HSA-156584
Alternative Protein Names 3'(2' -5'-Bisphosphate Nucleotidase 1 protein
3'-Phosphoadenosine 5'-Phosphate Phosphatase protein
Pap Phosphatase protein
Bisphosphate 3'-Nucleotidase 1 protein
Bpntase 1 protein
Hspip protein
Inositol-Polyphosphate 1-Phosphatase protein
BPNT1 protein

Information sourced from Uniprot.org

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