Human BPI protein (Recombinant-Active) (C-hFc-His) (STJP011895)

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STJP011895-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human BPI-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: BPI
Gene ID: 671
Uniprot ID: BPI_HUMAN
Immunogen Region: Val32-Lys487
Immunogen: Homo sapiens (Human)
Function The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Protein Name Bactericidal Permeability-Increasing Protein
Bpi
Cap 57
Database Links Reactome: R-HSA-166016
Reactome: R-HSA-6798695
Reactome: R-HSA-6803157
Cellular Localisation Secreted
Cytoplasmic Granule Membrane
Membrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules
Alternative Protein Names Bactericidal Permeability-Increasing Protein protein
Bpi protein
Cap 57 protein
BPI protein

Information sourced from Uniprot.org

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