Tissue Specificity | |
Post Translational Modifications | Autophosphorylated. |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. |
Protein Name | Bone Morphogenetic Protein Receptor Type-1bBmp Type-1b ReceptorBmpr-1bCd Antigen Cdw293 |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Bone Morphogenetic Protein Receptor Type-1b ELISA kitBmp Type-1b Receptor ELISA kitBmpr-1b ELISA kitCd Antigen Cdw293 ELISA kitBMPR1B ELISA kit |
output | |
Information sourced from Uniprot.org