Human BLOC1S6 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007435)

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STJP007435
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BLOC1S6-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BLOC1S6
Gene ID: 26258
Uniprot ID: BL1S6_HUMAN
Immunogen Region: Asp46-Met172
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated.
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.
Protein Name Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6
Bloc-1 Subunit 6
Pallid Protein Homolog
Pallidin
Syntaxin 13-Interacting Protein
Database Links Reactome: R-HSA-432722
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
It Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein
Alternative Protein Names Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 protein
Bloc-1 Subunit 6 protein
Pallid Protein Homolog protein
Pallidin protein
Syntaxin 13-Interacting Protein protein
BLOC1S6 protein
PA protein
PLDN protein

Information sourced from Uniprot.org