Post Translational Modifications | Phosphorylated. |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. |
Protein Name | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6Bloc-1 Subunit 6Pallid Protein HomologPallidinSyntaxin 13-Interacting Protein |
Database Links | Reactome: R-HSA-432722 |
Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinIt Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein |
Alternative Protein Names | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 proteinBloc-1 Subunit 6 proteinPallid Protein Homolog proteinPallidin proteinSyntaxin 13-Interacting Protein proteinBLOC1S6 proteinPA proteinPLDN protein |
Information sourced from Uniprot.org