Human BIN2 protein (Recombinant) (N-His) (STJP006367)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BIN2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | BIN2 |
| Gene ID | 51411 |
| Uniprot ID | BIN2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Asn244 |
Additional Info
| Function | Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis. |
| Protein Name | Bridging Integrator 2Breast Cancer-Associated Protein 1 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9673768 |
| Cellular Localisation | CytoplasmCell ProjectionPodosome MembranePeripheral Membrane ProteinCytoplasmic SideCell CortexPhagocytic CupAssociates With Membranes Enriched In PhosphoinositidesDetected In The Actin-Rich Cell Cortex At The Leading Edge Of Migrating CellsDetected At PodosomesAt An Actin-Rich Ring-Like Structure |
| Alternative Protein Names | Bridging Integrator 2 proteinBreast Cancer-Associated Protein 1 proteinBIN2 proteinBRAP1 protein |
Information sourced from Uniprot.org