Name: Human Betacellulin/BTC protein (Recombinant) (C-hFc) (STJP002897)
SKU: STJP002897
Availability: InStock

Human Betacellulin/BTC protein (Recombinant) (C-hFc) (STJP002897)

SKU:

STJP002897

$143.78 - $485.33

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	<0.1 EU/Mu g
Immunoreactivity:	Measured in a cell proliferation assay using BALB/3T3 mouse fibroblasts. The ED₅₀ for this effect is 1.02-4.06 ng/mL, corresponding to a specific activity of 2.46×10⁵~9.80×10⁵ units/mg.

Gene Symbol:	BTC
Gene ID:	685
Uniprot ID:	BTC_HUMAN
Immunogen Region:	Asp32-Tyr111
Immunogen:	Recombinant Human Betacellulin/BTC Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp32-Tyr111) of human Betacellulin/BTC (Accession #NP_001720.1) fused with and a hFc tag at the C-terminus.
Immunogen Sequence:	DGNSTRSPETNGLLCGDPEE NCAATTTQSKRKGHFSRCPK QYKHYCIKGRCRFVVAEQTP SCVCDEGYIGARCERVDLFY

Function	Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Protein Name	Probetacellulin Cleaved Into - Betacellulin Btc
Database Links	Reactome: R-HSA-1227986 Reactome: R-HSA-1236394 Reactome: R-HSA-1250196 Reactome: R-HSA-1250342 Reactome: R-HSA-1250347 Reactome: R-HSA-1251985 Reactome: R-HSA-1257604 Reactome: R-HSA-177929 Reactome: R-HSA-179812 Reactome: R-HSA-180292 Reactome: R-HSA-180336 Reactome: R-HSA-182971 Reactome: R-HSA-1963640 Reactome: R-HSA-1963642 Reactome: R-HSA-212718 Reactome: R-HSA-2219530 Reactome: R-HSA-5638303 Reactome: R-HSA-5673001 Reactome: R-HSA-6785631 Reactome: R-HSA-6811558 Reactome: R-HSA-8847993 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8863795 Reactome: R-HSA-9009391 Reactome: R-HSA-9634638 Reactome: R-HSA-9664565 Reactome: R-HSA-9665686
Cellular Localisation	Betacellulin: Secreted Extracellular Space Probetacellulin: Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Probetacellulin Cleaved Into - Betacellulin protein Btc protein BTC protein

Information sourced from Uniprot.org

Model	Name	Host
STJP002461	Human CD7 protein (Recombinant) (C-hFc) (STJP002461)	HEK293 cells
STJP001977	Human NBL1 protein (Recombinant) (C-hFc) (STJP001977)	HEK293 cells
STJP003003	Human GDF15 protein (Recombinant) (C-hFc) (STJP003003)	HEK293 cells
STJP002856	Human CD9 protein (Recombinant) (C-hFC) (STJP002856)	HEK293 cells
STJP001074	Human CD44 protein (Recombinant) (C-hFc&His) (STJP001074)	HEK293 cells

Human Betacellulin/BTC protein (Recombinant) (C-hFc) (STJP002897)

General Information