Human BCAS2 protein (Recombinant) (N-His) (STJP008061)

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STJP008061
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BCAS2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BCAS2
Gene ID: 10286
Uniprot ID: SPF27_HUMAN
Immunogen Region: Met1-Phe225
Immunogen: Homo sapiens (Human)
Function Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Protein Name Pre-Mrna-Splicing Factor Spf27
Breast Carcinoma-Amplified Sequence 2
Dna Amplified In Mammary Carcinoma 1 Protein
Spliceosome-Associated Protein Spf 27
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Nucleolus
Alternative Protein Names Pre-Mrna-Splicing Factor Spf27 protein
Breast Carcinoma-Amplified Sequence 2 protein
Dna Amplified In Mammary Carcinoma 1 Protein protein
Spliceosome-Associated Protein Spf 27 protein
BCAS2 protein
DAM1 protein

Information sourced from Uniprot.org