| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). |
| Protein Name | Pre-Mrna-Splicing Factor Spf27Breast Carcinoma-Amplified Sequence 2Dna Amplified In Mammary Carcinoma 1 ProteinSpliceosome-Associated Protein Spf 27 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Protein Names | Pre-Mrna-Splicing Factor Spf27 proteinBreast Carcinoma-Amplified Sequence 2 proteinDna Amplified In Mammary Carcinoma 1 Protein proteinSpliceosome-Associated Protein Spf 27 proteinBCAS2 proteinDAM1 protein |
Information sourced from Uniprot.org