| Short Description : | Recombinant-Human BAFF R/TNFRSF13C-hIgG-Tag protein was developed from hek293 cells and has a target region of hIgG-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Bioactivity |
| Host: | HEK293 Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA with Human BAFF. The ED50 range ≤ 0.7 ug/ml. |
| Gene Symbol: | TNFRSF13C |
| Gene ID: | 115650 |
| Uniprot ID: | TR13C_HUMAN |
| Accession Number: | NP_443177.1 |
| Immunogen: | Human |
| Immunogen Region: | 1-78aa |
| Immunogen Sequence: |
| Tissue Specificity | Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes. |
| Function | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 13cB-Cell-Activating Factor ReceptorBaff ReceptorBaff-RBlys Receptor 3Cd Antigen Cd268 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 13c proteinB-Cell-Activating Factor Receptor proteinBaff Receptor proteinBaff-R proteinBlys Receptor 3 proteinCd Antigen Cd268 proteinTNFRSF13C proteinBAFFR proteinBR3 protein |
Information sourced from Uniprot.org
