| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human BAFF-R (CD268)-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered solution in 0.5% glycine, 0.5% sucrose,.01% Tween80, mM Glutamic acid, pH7.5. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The ED (50) was determined by the ability to block BAFF induced survival of splenocyte cells, and was found to be in the range of.0-5.0 ug/ml. NA |
| Gene Symbol: |
TNFRSF13C |
| Gene ID: |
115650 |
| Uniprot ID: |
TR13C_HUMAN |
| Immunogen Region: |
ECD |
| Immunogen: |
DNA sequence encoding Human BAFF-R extracellular domain was expressed in HEK293 cells NA |
| Immunogen Sequence: |
MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPGLL FG APALLGLALV LALVLVGLVS WRRRQRRLRG ASSAEAPDGD NA |
| Tissue Specificity | Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes. |
| Function | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 13cB-Cell-Activating Factor ReceptorBaff ReceptorBaff-RBlys Receptor 3Cd Antigen Cd268 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 13c proteinB-Cell-Activating Factor Receptor proteinBaff Receptor proteinBaff-R proteinBlys Receptor 3 proteinCd Antigen Cd268 proteinTNFRSF13C proteinBAFFR proteinBR3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
