| Host: | HEK293 Cells |
| Applications: | SDS-PAGE/Bioactivity |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human B7-H6-hIgG-His-Tag protein was developed from hek293 cells and has a target region of hIgG-His-Tag. For use in research applications. |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA with Human NCR3. The ED50 range ≤500 ng/ml. |
| Gene Symbol: | NCR3LG1 |
| Gene ID: | 374383 |
| Uniprot ID: | NR3L1_HUMAN |
| Immunogen Region: | 25-262aa |
| Accession Number: | NP_001189368.1 |
| Immunogen: | Human |
| Immunogen Sequence: | DLKVEMMAGG TQITPLNDNV TIFCNIFYSQ PLNITSMGIT WFWKSLTFDK EVKVFEFFGD HQEAFRPGAI VSPWRLKSGD ASLRLPGIQL EEAGEYRCEV VVTPLKAQGT VQLEVVASPA SRLLLDQVGM KENEDKYMCE SSGFYPEAIN ITWEKQTQKF PHPIEISEDV ITGPTIKNMD GTFNVTSCLK LNSSQEDPGT VYQCVVRHAS LHTPLRSNFT LTAARHSL |
| Tissue Specificity | Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B-lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level). |
| Function | Triggers NCR3-dependent natural killer cell activation. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 3 Ligand 1B7 Homolog 6B7-H6 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Natural Cytotoxicity Triggering Receptor 3 Ligand 1 proteinB7 Homolog 6 proteinB7-H6 proteinNCR3LG1 proteinB7H6 protein |
Information sourced from Uniprot.org