Human B7-H5/Gi24/VISTA protein (Recombinant) (C-His) (STJP001028)

Human B7-H5/Gi24/VISTA protein (Recombinant) (C-His) (STJP001028)

SKU:
STJP001028
£139.50 - £291.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: VSIR
Gene ID: 64115
Uniprot ID: VISTA_HUMAN
Immunogen: Recombinant Human B7-H5/Gi24/VISTA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe 33-Ala 194 ) of human VISTA/B7-H5/PD-1H (Accession #AAH20568.1) fused with a 6×His tag at the C-terminus.
Immunogen Sequence: FKVATPYSLYVCPEGQNVTL TCRLLGPVDKGHDVTFYKTW YRSSRGEVQTCSERRPIRNL TFQDLHLHHGGHQAANTSHD LAQRHGLESASDHHGNFSIT MRNLTLLDSGLYCCLVVEIR HHHSEHRVHGAMELQVQTGK DAPSNCVVYPSSSQESENIT AA
Post Translational Modifications At the cell surface, may be cleaved by MMP14. N-glycosylated.
Function Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation.
Protein Name V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation
Platelet Receptor Gi24
Stress-Induced Secreted Protein-1
Sisp-1
V-Set Domain-Containing Immunoregulatory Receptor
V-Set Immunoregulatory Receptor
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation protein
Platelet Receptor Gi24 protein
Stress-Induced Secreted Protein-1 protein
Sisp-1 protein
V-Set Domain-Containing Immunoregulatory Receptor protein
V-Set Immunoregulatory Receptor protein
VSIR protein
C10orf54 protein
SISP1 protein
VISTA protein
PP2135 protein
UNQ730 protein
PRO1412 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP001100 Human B7-H5/Gi24/VISTA protein (Recombinant) (C-hFc&His) (STJP001100) HEK293 cells
STJP001321 Mouse B7-H5/Gi24/VISTA protein (Recombinant) (C-His) (STJP001321) HEK293 cells
STJP000989 Human B7-H4/VTCN1 protein (Recombinant) (C-His) (STJP000989) HEK293 cells
STJP002549 Human B7-1/CD80 protein (Recombinant) (C-His) (STJP002549) HEK293 cells
STJP002560 Human B7-2/CD86 protein (Recombinant) (C-His) (STJP002560) HEK293 cells
STJP002683 Human B7-H3/CD276 protein (Recombinant) (C-His) (STJP002683) HEK293 cells
STJP001350 Human B7-H6/NCR3LG1 protein (Recombinant) (C-His) (STJP001350) HEK293 cells
STJP001363 Human B7-H3/CD276 protein (Recombinant) (C-hFc&His) (STJP001363) HEK293 cells
!