Human B7-H5/Gi24/VISTA protein (Recombinant) (C-His) (STJP001028)

SKU:

STJP001028

£72.50 - £156.50

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human B7-H5/Gi24/VISTA-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:

Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.

Gene Symbol:	VSIR
Gene ID:	64115
Uniprot ID:	VISTA_HUMAN
Immunogen:	Recombinant Human B7-H5/Gi24/VISTA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe 33-Ala 194 ) of human VISTA/B7-H5/PD-1H (Accession #AAH20568.1) fused with a 6×His tag at the C-terminus.

Post Translational Modifications	At the cell surface, may be cleaved by MMP14. N-glycosylated.
Function	Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation.
Protein Name	V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation Platelet Receptor Gi24 Stress-Induced Secreted Protein-1 Sisp-1 V-Set Domain-Containing Immunoregulatory Receptor V-Set Immunoregulatory Receptor
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation protein Platelet Receptor Gi24 protein Stress-Induced Secreted Protein-1 protein Sisp-1 protein V-Set Domain-Containing Immunoregulatory Receptor protein V-Set Immunoregulatory Receptor protein VSIR protein C10orf54 protein SISP1 protein VISTA protein PP2135 protein UNQ730 protein PRO1412 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance