• Biotinylated Human B7-H2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human B7-H2 is greater than 95% as determined by SEC-HPLC.
  • Immobilized Human ICOS (C136S, C137S) , His Tag at 1 Mu g/ml (100 Mu l/Well) on the plate. Dose response curve for Biotinylated Human B7-H2, His Tag with the EC50 of 0. 24 Mu g/ml determined by ELISA.

Human B7-H2/ICOSLG protein (Recombinant) (C-His-Avi) {Biotin} (STJP001675)

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STJP001675

£618.50 - £1,909.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human B7-H2/ICOSLG-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: ICOSLG
Gene ID: 23308
Uniprot ID: ICOSL_HUMAN
Immunogen Region: Asp19-Ser258
Immunogen: DNA sequence encoding Human B7-H2/ICOSLG including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Protein Name Icos Ligand
B7 Homolog 2
B7-H2
B7-Like Protein Gl50
B7-Related Protein 1
B7rp-1
Cd Antigen Cd275
Database Links Reactome: R-HSA-388841
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Icos Ligand protein
B7 Homolog 2 protein
B7-H2 protein
B7-Like Protein Gl50 protein
B7-Related Protein 1 protein
B7rp-1 protein
Cd Antigen Cd275 protein
ICOSLG protein
B7H2 protein
B7RP1 protein
ICOSL protein
KIAA0653 protein

Information sourced from Uniprot.org

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