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Human B7-1/CD80 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001714)

Biotinylated Human B7-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human B7-1 is greater than 95% as determined by SEC-HPLC.
Immobilized Human CTLA-4, hFc Tag at 2 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Biotinylated Human B7-1, His Tag with the EC50 of 1. 9 Mu g/ml determined by ELISA.

Human B7-1/CD80 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001714)

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STJP001714

£618.50 - £1,909.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human B7-1/CD80-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.

Conjugation:	Biotin
Formulation:	Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range:	Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction:	The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).

Gene Symbol:	CD80
Gene ID:	941
Uniprot ID:	CD80_HUMAN
Immunogen Region:	Val35-Asn242
Immunogen:	DNA sequence encoding Human B7-1/CD80 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.

Function	Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Protein Name	T-Lymphocyte Activation Antigen Cd80 Activation B7-1 Antigen Bb1 Ctla-4 Counter-Receptor B7.1 B7 Cd Antigen Cd80
Database Links	Reactome: R-HSA-1257604 Reactome: R-HSA-2219530 Reactome: R-HSA-389356 Reactome: R-HSA-389357 Reactome: R-HSA-389359 Reactome: R-HSA-389513 Reactome: R-HSA-6783783 Reactome: R-HSA-6811558
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	T-Lymphocyte Activation Antigen Cd80 protein Activation B7-1 Antigen protein Bb1 protein Ctla-4 Counter-Receptor B7.1 protein B7 protein Cd Antigen Cd80 protein CD80 protein CD28LG protein CD28LG1 protein LAB7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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