Human B4GALT5 protein (Recombinant) (N-His) (STJP010664)

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STJP010664
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human B4GALT5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: B4GALT5
Gene ID: 9334
Uniprot ID: B4GT5_HUMAN
Immunogen Region: Glu131-Tyr388
Immunogen: Homo sapiens (Human)
Function Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.
Protein Name Beta-1 -4-Galactosyltransferase 5
Beta-1 -4-Galtase 5
Beta4gal-T5
B4gal-T5
Beta-1 -4-Galt Ii
Glucosylceramide Beta-1 -4-Galactosyltransferase
Lactosylceramide Synthase
Laccer Synthase
Udp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5
Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5
Database Links Reactome: R-HSA-2022854
Reactome: R-HSA-913709
Reactome: R-HSA-975577
Reactome: R-HSA-9840309
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Trans Cisternae Of Golgi Stack
Alternative Protein Names Beta-1 -4-Galactosyltransferase 5 protein
Beta-1 -4-Galtase 5 protein
Beta4gal-T5 protein
B4gal-T5 protein
Beta-1 -4-Galt Ii protein
Glucosylceramide Beta-1 -4-Galactosyltransferase protein
Lactosylceramide Synthase protein
Laccer Synthase protein
Udp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5 protein
Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 protein
B4GALT5 protein

Information sourced from Uniprot.org

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