| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ATP6V1C1-N-His-SUMO & C-Strep protein was developed from e.coli and has a target region of N-His-SUMO & C-Strep. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ATP6V1C1 |
| Gene ID: | 528 |
| Uniprot ID: | VATC1_HUMAN |
| Immunogen Region: | Lys156-Glu256 |
| Immunogen: | Homo sapiens (Human) |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. |
| Protein Name | V-Type Proton Atpase Subunit C 1V-Atpase Subunit C 1Vacuolar Proton Pump Subunit C 1 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePeripheral Membrane ProteinClathrin-Coated Vesicle Membrane |
| Alternative Protein Names | V-Type Proton Atpase Subunit C 1 proteinV-Atpase Subunit C 1 proteinVacuolar Proton Pump Subunit C 1 proteinATP6V1C1 proteinATP6C proteinATP6D proteinVATC protein |
Information sourced from Uniprot.org