Human ATP2A1 protein (Recombinant) (N-His) (STJP008058)

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STJP008058
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ATP2A1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ATP2A1
Gene ID: 487
Uniprot ID: AT2A1_HUMAN
Immunogen Region: Thr357-Leu600
Immunogen: Homo sapiens (Human)
Function Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Protein Name Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1
Serca1
Sr Ca(2+-Atpase 1
Calcium Pump 1
Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform
Endoplasmic Reticulum Class 1/2 Ca(2+ Atpase
Database Links Reactome: R-HSA-1912420
Reactome: R-HSA-418359
Reactome: R-HSA-5578775
Reactome: R-HSA-936837
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Sarcoplasmic Reticulum Membrane
Alternative Protein Names Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1 protein
Serca1 protein
Sr Ca(2+-Atpase 1 protein
Calcium Pump 1 protein
Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform protein
Endoplasmic Reticulum Class 1/2 Ca(2+ Atpase protein
ATP2A1 protein

Information sourced from Uniprot.org

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