Human ATF3 protein (Recombinant) (No-Tag) (STJP017262)

SKU:
STJP017262
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ATF3-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATF3
Gene ID: 467
Uniprot ID: ATF3_HUMAN
Immunogen Region: 1-181aa
Accession Number: NP_001665
Immunogen: Human
Immunogen Sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2: Activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Isoform 3: Stress-induced isoform, counteracts the transcriptional repression of isoform 1.
Protein Name Cyclic Amp-Dependent Transcription Factor Atf-3
Camp-Dependent Transcription Factor Atf-3
Activating Transcription Factor 3
Database Links Reactome: R-HSA-380994
Reactome: R-HSA-9633012
Reactome: R-HSA-9648895
Cellular Localisation Nucleus
Alternative Protein Names Cyclic Amp-Dependent Transcription Factor Atf-3 protein
Camp-Dependent Transcription Factor Atf-3 protein
Activating Transcription Factor 3 protein
ATF3 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP004231 Human ATF3 protein (Recombinant) (N-GST) (STJP004231) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP018664 Human BATF3 protein (Recombinant) (His-Tag) (STJP018664) E.coli SDS-PAGE
STJP015162 Human PTHLH, no tag protein (Recombinant) (No tag) (STJP015162) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP000828 Human TNFSF15 protein (Recombinant) (No tag) (STJP000828) E.coli
STJP019974 Human CD47 protein (Recombinant) (No Tag) (STJP019974) HEK293 cells

Related Products

!