Human ATAT1 protein (Recombinant) (N-His) (STJP005556)

SKU:
STJP005556
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ATAT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ATAT1
Gene ID: 79969
Uniprot ID: ATAT_HUMAN
Immunogen Region: Met1-Pro196
Immunogen: Homo sapiens (Human)
Function Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics.this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
Protein Name Alpha-Tubulin N-Acetyltransferase 1
Alpha-Tat
Alpha-Tat1
Tat
Acetyltransferase Mec-17 Homolog
Database Links Reactome: R-HSA-5617833
Cellular Localisation Cytoplasm
Membrane
Clathrin-Coated Pit
Cell Junction
Focal Adhesion
Cell Projection
Axon
Cytoskeleton
Spindle
Alternative Protein Names Alpha-Tubulin N-Acetyltransferase 1 protein
Alpha-Tat protein
Alpha-Tat1 protein
Tat protein
Acetyltransferase Mec-17 Homolog protein
ATAT1 protein
C6orf134 protein
MEC17 protein
Nbla00487 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005557 Human ATAT1 protein (Recombinant) (C-His) (STJP005557) E. coli
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP002980 Human KLHL20 protein (Recombinant) (N-His) (STJP002980) HEK293 cells
STJP003027 Human CCL3L1 protein (Recombinant) (N-His) (STJP003027) HEK293 cells

Related Products

!