Human ATAD2 protein (Recombinant) (N-His) (STJP005590)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ATAD2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ATAD2 |
| Gene ID | 29028 |
| Uniprot ID | ATAD2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser245-Glu396 |
Additional Info
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
| Protein Name | Atpase Family Aaa Domain-Containing Protein 2Aaa Nuclear Coregulator Cancer-Associated ProteinAncca |
| Database Links | Reactome: R-HSA-8866910 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Atpase Family Aaa Domain-Containing Protein 2 proteinAaa Nuclear Coregulator Cancer-Associated Protein proteinAncca proteinATAD2 proteinL16 proteinPRO2000 protein |
Information sourced from Uniprot.org