Human ATAD2 protein (Recombinant) (N-His) (STJP005590)

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STJP005590
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ATAD2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ATAD2
Gene ID: 29028
Uniprot ID: ATAD2_HUMAN
Immunogen Region: Ser245-Glu396
Immunogen: Homo sapiens (Human)
Function May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
Protein Name Atpase Family Aaa Domain-Containing Protein 2
Aaa Nuclear Coregulator Cancer-Associated Protein
Ancca
Database Links Reactome: R-HSA-8866910
Cellular Localisation Nucleus
Alternative Protein Names Atpase Family Aaa Domain-Containing Protein 2 protein
Aaa Nuclear Coregulator Cancer-Associated Protein protein
Ancca protein
ATAD2 protein
L16 protein
PRO2000 protein

Information sourced from Uniprot.org

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