Human ASPH protein (Recombinant) (N-His) (STJP005253)

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STJP005253
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ASPH-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ASPH
Gene ID: 444
Uniprot ID: ASPH_HUMAN
Immunogen Region: Asp101-Thr270
Immunogen: Homo sapiens (Human)
Function Isoform 1: Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. Isoform 8: Membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.
Protein Name Aspartyl/Asparaginyl Beta-Hydroxylase
Aspartate Beta-Hydroxylase
Asp Beta-Hydroxylase
Peptide-Aspartate Beta-Dioxygenase
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-5578775
Reactome: R-HSA-9629569
Cellular Localisation Isoform 1: Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Isoform 4: Sarcoplasmic Reticulum Membrane
Isoform 8: Endoplasmic Reticulum Membrane
Alternative Protein Names Aspartyl/Asparaginyl Beta-Hydroxylase protein
Aspartate Beta-Hydroxylase protein
Asp Beta-Hydroxylase protein
Peptide-Aspartate Beta-Dioxygenase protein
ASPH protein
BAH protein

Information sourced from Uniprot.org