Human AS3MT protein (Recombinant) (His-Tag) (STJP017665)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human AS3MT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.15M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AS3MT |
| Gene ID | 57412 |
| Uniprot ID | AS3MT_HUMAN |
| Accession Number | NP_065733 |
| Immunogen | Human |
| Immunogen Region | 1-375aa |
| Immunogen Sequence |
Additional Info
| Function | Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH. |
| Protein Name | Arsenite MethyltransferaseMethylarsonite MethyltransferaseS-Adenosyl-L-Methionine -Arsenic(Iii Methyltransferase |
| Database Links | Reactome: R-HSA-156581 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Arsenite Methyltransferase proteinMethylarsonite Methyltransferase proteinS-Adenosyl-L-Methionine -Arsenic(Iii Methyltransferase proteinAS3MT proteinCYT19 protein |
Information sourced from Uniprot.org