Function | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. |
Protein Name | Adp-Ribosylation Factor-Like Protein 4cAdp-Ribosylation Factor-Like Protein 7Adp-Ribosylation Factor-Like Protein Lak |
Database Links | Reactome: R-HSA-9029569 |
Cellular Localisation | Cell ProjectionFilopodiumCell MembraneCytoplasm |
Alternative Protein Names | Adp-Ribosylation Factor-Like Protein 4c proteinAdp-Ribosylation Factor-Like Protein 7 proteinAdp-Ribosylation Factor-Like Protein Lak proteinARL4C proteinARL7 protein |
Information sourced from Uniprot.org