Human ARL4C protein (Recombinant) (N-His) (STJP008346)

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STJP008346
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ARL4C-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ARL4C
Gene ID: 10123
Uniprot ID: ARL4C_HUMAN
Immunogen Region: Ser13-Arg192
Immunogen: Homo sapiens (Human)
Function Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.
Protein Name Adp-Ribosylation Factor-Like Protein 4c
Adp-Ribosylation Factor-Like Protein 7
Adp-Ribosylation Factor-Like Protein Lak
Database Links Reactome: R-HSA-9029569
Cellular Localisation Cell Projection
Filopodium
Cell Membrane
Cytoplasm
Alternative Protein Names Adp-Ribosylation Factor-Like Protein 4c protein
Adp-Ribosylation Factor-Like Protein 7 protein
Adp-Ribosylation Factor-Like Protein Lak protein
ARL4C protein
ARL7 protein

Information sourced from Uniprot.org