Name: Human ARHGEF25 protein (Recombinant) (N-His) (STJP007565)
SKU: STJP007565
Availability: InStock

Human ARHGEF25 protein (Recombinant) (N-His) (STJP007565)

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STJP007565

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ARHGEF25-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis.
Protein Name	Rho Guanine Nucleotide Exchange Factor 25 Guanine Nucleotide Exchange Factor Geft Rac/Cdc42/Rho Exchange Factor Geft Rhoa/Rac/Cdc42 Guanine Nucleotide Exchange Factor Geft P63rhogef
Database Links	Reactome: R-HSA-416476 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149
Cellular Localisation	Cell Membrane Cytoplasm Myofibril Sarcomere Highly Colocalizes With Actin Regions
Alternative Protein Names	Rho Guanine Nucleotide Exchange Factor 25 protein Guanine Nucleotide Exchange Factor Geft protein Rac/Cdc42/Rho Exchange Factor Geft protein Rhoa/Rac/Cdc42 Guanine Nucleotide Exchange Factor Geft protein P63rhogef protein ARHGEF25 protein GEFT protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP001380	Human TET2 protein (Recombinant) (N-his) (STJP001380)	HEK293 cells
STJP010338	Human LGI1 protein (Recombinant) (N-His) (STJP010338)	E. coli
STJP011346	Human MMAB protein (Recombinant) (N-His) (STJP011346)	E. coli

Human ARHGEF25 protein (Recombinant) (N-His) (STJP007565)

General Information