Human AQP7 protein (Recombinant) (N-GST) (STJP003180)

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STJP003180
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AQP7-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AQP7
Gene ID: 364
Uniprot ID: AQP7_HUMAN
Immunogen Region: Leu68-Gly122
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylation by PKA could prevent the interaction with PLIN1.
Function Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels.
Protein Name Aquaporin-7
Aqp-7
Aquaglyceroporin-7
Aquaporin Adipose
Aqpap
Aquaporin-7-Like
Database Links Reactome: R-HSA-432030
Reactome: R-HSA-432047
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Lipid Droplet
Internalized From The Cell Membrane In Response To Catecholamine-Induced Activation Of Pka
Detected On Intracellular Membranes And Colocalizes With Lipid Droplets
Colocalizes With Plin1 In Adipocytes
Probably On Lipid Droplets
Alternative Protein Names Aquaporin-7 protein
Aqp-7 protein
Aquaglyceroporin-7 protein
Aquaporin Adipose protein
Aqpap protein
Aquaporin-7-Like protein
AQP7 protein
AQP7L protein
AQP9 protein

Information sourced from Uniprot.org

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