Human API5 protein (Recombinant) (N-His) (STJP005964)

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STJP005964
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Short Description :Recombinant-Human API5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:API5
Gene ID:8539
Uniprot ID:API5_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Pro2-Phe360
Post Translational Modifications Acetylation at Lys-251 impairs antiapoptotic function.
Function Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Protein Name Apoptosis Inhibitor 5
Api-5
Antiapoptosis Clone 11 Protein
Aac-11
Cell Migration-Inducing Gene 8 Protein
Fibroblast Growth Factor 2-Interacting Factor
Fif
Protein Xagl
Database Links
Cellular Localisation Nucleus
Cytoplasm
Mainly Nuclear
Can Also Be Cytoplasmic
Isoform 3: Cytoplasm
Alternative Protein Names Apoptosis Inhibitor 5 protein
Api-5 protein
Antiapoptosis Clone 11 Protein protein
Aac-11 protein
Cell Migration-Inducing Gene 8 Protein protein
Fibroblast Growth Factor 2-Interacting Factor protein
Fif protein
Protein Xagl protein
API5 protein
MIG8 protein

Information sourced from Uniprot.org

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