Human AP4M1 protein (Recombinant) (N-His) (STJP016383)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AP4M1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | AP4M1 |
| Gene ID | 9179 |
| Uniprot ID | AP4M1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys184-Ile453 |
Additional Info
| Function | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal. |
| Protein Name | Ap-4 Complex Subunit Mu-1Ap-4 Adaptor Complex Mu SubunitAdaptor-Related Protein Complex 4 Subunit Mu-1Mu Subunit Of Ap-4Mu-Adaptin-Related Protein 2Mu-Arp2Mu4-AdaptinMu4 |
| Database Links | Reactome: R-HSA-432720 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinEarly EndosomeFound In Soma And Dendritic Shafts Of Neuronal Cells |
| Alternative Protein Names | Ap-4 Complex Subunit Mu-1 proteinAp-4 Adaptor Complex Mu Subunit proteinAdaptor-Related Protein Complex 4 Subunit Mu-1 proteinMu Subunit Of Ap-4 proteinMu-Adaptin-Related Protein 2 proteinMu-Arp2 proteinMu4-Adaptin proteinMu4 proteinAP4M1 proteinMUARP2 protein |
Information sourced from Uniprot.org