Human ANXA13 protein (Recombinant) (N-His) (STJP004450)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ANXA13-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ANXA13 |
| Gene ID | 312 |
| Uniprot ID | ANX13_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-His316 |
Additional Info
| Function | Isoform A: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup. Isoform B: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium. |
| Protein Name | Annexin A13Annexin XiiiAnnexin-13Intestine-Specific AnnexinIsa |
| Database Links | |
| Cellular Localisation | Apical Cell MembraneCell MembraneLipid-AnchorCytoplasmic VesicleMyristoylation Anchors The Protein To The MembraneBut The Protein Also Displays Calcium-DependentReversible Binding To Lipid MembranesAssociated With The Plasma Membrane Of UndifferentiatedProliferating Crypt Epithelial Cells As Well As Differentiated Villus Enterocytes |
| Alternative Protein Names | Annexin A13 proteinAnnexin Xiii proteinAnnexin-13 proteinIntestine-Specific Annexin proteinIsa proteinANXA13 proteinANX13 protein |
Information sourced from Uniprot.org