Human ANXA13 protein (Recombinant) (N-His) (STJP004450)

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STJP004450
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ANXA13-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ANXA13
Gene ID: 312
Uniprot ID: ANX13_HUMAN
Immunogen Region: Met1-His316
Immunogen: Homo sapiens (Human)
Function Isoform A: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup. Isoform B: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium.
Protein Name Annexin A13
Annexin Xiii
Annexin-13
Intestine-Specific Annexin
Isa
Cellular Localisation Apical Cell Membrane
Cell Membrane
Lipid-Anchor
Cytoplasmic Vesicle
Myristoylation Anchors The Protein To The Membrane
But The Protein Also Displays Calcium-Dependent
Reversible Binding To Lipid Membranes
Associated With The Plasma Membrane Of Undifferentiated
Proliferating Crypt Epithelial Cells As Well As Differentiated Villus Enterocytes
Alternative Protein Names Annexin A13 protein
Annexin Xiii protein
Annexin-13 protein
Intestine-Specific Annexin protein
Isa protein
ANXA13 protein
ANX13 protein

Information sourced from Uniprot.org

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